Our proprietary, innovative and patented K-One® surface chemistry is the culmination of over 10 years of academic research led at Paris-Saclay University, setting a new standard for surface treatment effectiveness.
Figure 1 - Ligands bind spontaneously and in a random fashion to the surface of gold nanoparticles or chips, resulting in less than 20-30% of the ligands being functional.
Figure 2 - By coating the gold surface with K-One® chemistry, we control the ligands’ exposure, orientation, density, and distribution, resulting in more than 90% of the ligands being functional, while the surface is fully protected from undesired interactions.
A major challenge for rapid test developers is to achieve sensitivity at the limits of the readers' capacities without compromising the specificity of the assay. Ultimately, the tests need to be highly reproducible, regardless of the complexity of the biological matrix.
High-performance: we enhance sensitivity, specificity, and selectivity, achieving up to a 10x improvement in limit of detection (LoD) compared to the standard methods and drastically reducing the number of false positives
Reproducibility: we ensure repeatable and reliable results for LFA, even when working with complex samples
Methodology: we propose a unique screening and bioconjugation methodology tailored to your biomolecules and assays: FirstTimeRight (FTR) approach
Explore our benchmark study
For biotech and pharmaceutical companies engaged in screening and characterizing biomolecules, immobilizing large ligands, such as antibodies, is a well-established process. However, significant challenges arise when working with certain proteins and smaller ligands, where the stability of ligand attachment on the chip becomes a critical concern. Additionally, background noise can further complicate the task, obscuring data and making it challenging to obtain meaningful insights.
Limitless: we can immobilize any type of ligands on SPR sensor chips
Robustness: biomolecules remain firmly attached even through repeated cycles of SPR analysis
Background noise reduction: we achieve a significant enhancement in Signal to Noise Ratio (SNR)
Lateral Flow Assays and other nanoparticle-based assays
Biomolecule screening & characterization by SPR/SPRi